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Active Grants

Sleep Deprivation: How does it exacerbate seizures and if so can they be prevented?

Lily's Grace Grant
PI: Rama Maganti, MD
Study aims to understand how sleep deprivation exacerbates seizures in epilepsy
7/1/2016 - 6/30/2018

Cannabidiol, mTOR and the excitation/inhibition balance in epilepsy

Epilepsy Foundation
Targeted Research Initiative
PI: Rama Maganti, MD
Understanding the mechanism behind CBD’s anticonvulsant potential will inform neurologists as to the appropriate patient groups and epilepsy syndromes which would potentially be alleviated by CBD.
1/1/2017 - 12/31/2018

Reduced GABAergic Tonic Inhibition as a Shared Mechanism of Post-Traumatic Sleep Disorders and Epilpesy

Department of Defense (CDMRP)
PI: Rama Maganti, MD
This application will focus on whether post-traumatic sleep disorders and post-traumatic epilepsy evolve following TBI sharing a common mechanism in the brain.
7/1/17 – 12/31/18

Sleep deprivation-induced seizure exacerbation: Targeting tonic inhibition as a therapeutic strategy.

PI: Rama Maganti, M.D.
05/01/2018 - 4/30/2020