My research aims at combining neuroimaging techniques such as PET, functional MRI, TMS-EEG, and high-density EEG to a theoretical framework, the Integrated Information Theory of Consciousness, hoping to uncover the neural mechanisms of the level and contents of consciousness in healthy subjects and neurological patients. I am board certified in neurology in both Europe and the US.
| Quantitative spatio-temporal characterization of epileptic spikes using high density EEG: Differences between NREM sleep and REM sleep Kang X, Boly M, Findlay G, Jones B, Gjini K, Maganti R, Struck AF. Sci Rep. 2020 Feb 3;10(1):1673. doi: 10.1038/s41598-020-58612-4. See full publication information |
| The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting Provencio JJ, Hemphill JC, Claassen J, Edlow BL, Helbok R, Vespa PM, Diringer MN, Polizzotto L, Shutter L, Suarez JI, Stevens RD, Hanley DF, Akbari Y, Bleck TP, Boly M, Foreman B, Giacino JT, Hartings JA, Human T, Kondziella D, Ling GSF, Mayer SA, McNett M, Menon DK, Meyfroidt G, Monti MM, Park S, Pouratian N, Puybasset L, Rohaut B, Rosenthal ES, Schiff ND, Sharshar T, Wagner A, Whyte J, Olson DM; Neurocritical Care Society Curing Coma Campaign. Neurocrit Care. 2020 Aug;33(1):1-12. doi: 10.1007/s12028-020-01028-9. See full publication information |
| The spectral exponent of the resting EEG indexes the presence of consciousness during unresponsiveness induced by propofol, xenon, and ketamine Colombo MA, Napolitani M, Boly M, Gosseries O, Casarotto S, Rosanova M, Brichant JF, Boveroux P, Rex S, Laureys S, Massimini M, Chieregato A, Sarasso S. Neuroimage. 2019 Apr 1;189:631-644. doi: 10.1016/j.neuroimage.2019.01.024. Epub 2019 Jan 11. See full publication information |
| Increased lucid dream frequency in long-term meditators but not following MBSR training Baird B, Riedner BA, Boly M, Davidson RJ, Tononi G. Psychol Conscious (Wash D C). 2019 Mar;6(1):40-54. doi: 10.1037/cns0000176. Epub 2018 Nov 29. See full publication information |
| Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS-EEG study Lee M, Baird B, Gosseries O, Nieminen JO, Boly M, Postle BR, Tononi G, Lee SW. Sci Rep. 2019 Mar 26;9(1):5175. doi: 10.1038/s41598-019-41274-2. See full publication information |
| Slowing less than 1 Hz is decreased near the seizure onset zone Lundstrom BN, Boly M, Duckrow R, Zaveri HP, Blumenfeld H. Sci Rep. 2019 Apr 17;9(1):6218. doi: 10.1038/s41598-019-42347-y. See full publication information |
| Changes in Whole Brain Dynamics and Connectivity Patterns during Sevoflurane- and Propofol-induced Unconsciousness Identified by Functional Magnetic Resonance Imaging Golkowski D, Larroque SK, Vanhaudenhuyse A, Plenevaux A, Boly M, Di Perri C, Ranft A, Schneider G, Laureys S, Jordan D, Bonhomme V, Ilg R. Anesthesiology. 2019 Jun;130(6):898-911. doi: 10.1097/ALN.0000000000002704. See full publication information |
| A fast and general method to empirically estimate the complexity of brain responses to transcranial and intracranial stimulations Comolatti R, Pigorini A, Casarotto S, Fecchio M, Faria G, Sarasso S, Rosanova M, Gosseries O, Boly M, Bodart O, Ledoux D, Brichant JF, Nobili L, Laureys S, Tononi G, Massimini M, Casali AG. Brain Stimul. 2019 Sep-Oct;12(5):1280-1289. doi: 10.1016/j.brs.2019.05.013. Epub 2019 May 15. See full publication information |
| Optimization of the Cortical Traveling Wave Analysis framework for feasibility in Stereo-Electroencephalography Coelli S, Nobili L, Boly M, Riedner B, Bianchi AM. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:3854-3857. doi: 10.1109/EMBC.2019.8857664. See full publication information |
| Graph Theoretical Analysis of Cortical Networks based on Conscious Experience Lee M, Baird B, Gosseries O, Nieminen JO, Boly M, Tononi G, Lee SW. Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:3373-3376. doi: 10.1109/EMBC.2019.8857648. See full publication information |
| Electroencephalography and single-unit recordings Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 1K23NS112473-01A1 PI: BOLY, MELANIE 12/15/2020 - 11/30/2025 |
| Identifying the neural mechanisms of loss of consciousness during sleep using intracranial recordings in humans
Sponsor: TEMPLETON WORLD CHARITY FDN Award: TWCF-2022-30258 PI: Boly,Melanie; 01/01/2023 - 12/31/2025 |
| Accelerating research on consciousness
Sponsor: UNIVERSITEIT VAN AMSTERDAM Award: C2328.0527 TWCF0646 PI: Boly,Melanie; 03/01/2022 - 10/01/2026 |
| In vivo Imaging of Glymphatic Circulation: Measurement of Brain Interstitial Fluid Flow During Wake and Sleep with Ultra-High Performance MRI
Sponsor: GE GLOBAL RESEARCH Award: 401180352 PI: Boly,Melanie; 08/15/2022 - 08/14/2025 |
| Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU
Sponsor: MASSACHUSETTS GENERAL HOSPITAL Award: 246047 PI: Boly,Melanie; 08/01/2024 - 05/31/2025 |
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