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Boly Lab

Boly Lab

Melanie Boly, M.D., Ph.D.
Melanie Boly, M.D., Ph.D.

My research aims at combining neuroimaging techniques such as PET, functional MRI, TMS-EEG, and high-density EEG to a theoretical framework, the Integrated Information Theory of Consciousness, hoping to uncover the neural mechanisms of the level and contents of consciousness in healthy subjects and neurological patients. I am board certified in neurology in both Europe and the US.

Quantitative spatio-temporal characterization of epileptic spikes using high density EEG: Differences between NREM sleep and REM sleep
Kang X, Boly M, Findlay G, Jones B, Gjini K, Maganti R, Struck AF.
Sci Rep. 2020 Feb 3;10(1):1673. doi: 10.1038/s41598-020-58612-4.
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The Curing Coma Campaign: Framing Initial Scientific Challenges-Proceedings of the First Curing Coma Campaign Scientific Advisory Council Meeting
Provencio JJ, Hemphill JC, Claassen J, Edlow BL, Helbok R, Vespa PM, Diringer MN, Polizzotto L, Shutter L, Suarez JI, Stevens RD, Hanley DF, Akbari Y, Bleck TP, Boly M, Foreman B, Giacino JT, Hartings JA, Human T, Kondziella D, Ling GSF, Mayer SA, McNett M, Menon DK, Meyfroidt G, Monti MM, Park S, Pouratian N, Puybasset L, Rohaut B, Rosenthal ES, Schiff ND, Sharshar T, Wagner A, Whyte J, Olson DM; Neurocritical Care Society Curing Coma Campaign.
Neurocrit Care. 2020 Aug;33(1):1-12. doi: 10.1007/s12028-020-01028-9.
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The spectral exponent of the resting EEG indexes the presence of consciousness during unresponsiveness induced by propofol, xenon, and ketamine
Colombo MA, Napolitani M, Boly M, Gosseries O, Casarotto S, Rosanova M, Brichant JF, Boveroux P, Rex S, Laureys S, Massimini M, Chieregato A, Sarasso S.
Neuroimage. 2019 Apr 1;189:631-644. doi: 10.1016/j.neuroimage.2019.01.024. Epub 2019 Jan 11.
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Increased lucid dream frequency in long-term meditators but not following MBSR training
Baird B, Riedner BA, Boly M, Davidson RJ, Tononi G.
Psychol Conscious (Wash D C). 2019 Mar;6(1):40-54. doi: 10.1037/cns0000176. Epub 2018 Nov 29.
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Connectivity differences between consciousness and unconsciousness in non-rapid eye movement sleep: a TMS-EEG study
Lee M, Baird B, Gosseries O, Nieminen JO, Boly M, Postle BR, Tononi G, Lee SW.
Sci Rep. 2019 Mar 26;9(1):5175. doi: 10.1038/s41598-019-41274-2.
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Slowing less than 1 Hz is decreased near the seizure onset zone
Lundstrom BN, Boly M, Duckrow R, Zaveri HP, Blumenfeld H.
Sci Rep. 2019 Apr 17;9(1):6218. doi: 10.1038/s41598-019-42347-y.
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Changes in Whole Brain Dynamics and Connectivity Patterns during Sevoflurane- and Propofol-induced Unconsciousness Identified by Functional Magnetic Resonance Imaging
Golkowski D, Larroque SK, Vanhaudenhuyse A, Plenevaux A, Boly M, Di Perri C, Ranft A, Schneider G, Laureys S, Jordan D, Bonhomme V, Ilg R.
Anesthesiology. 2019 Jun;130(6):898-911. doi: 10.1097/ALN.0000000000002704.
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A fast and general method to empirically estimate the complexity of brain responses to transcranial and intracranial stimulations
Comolatti R, Pigorini A, Casarotto S, Fecchio M, Faria G, Sarasso S, Rosanova M, Gosseries O, Boly M, Bodart O, Ledoux D, Brichant JF, Nobili L, Laureys S, Tononi G, Massimini M, Casali AG.
Brain Stimul. 2019 Sep-Oct;12(5):1280-1289. doi: 10.1016/j.brs.2019.05.013. Epub 2019 May 15.
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Optimization of the Cortical Traveling Wave Analysis framework for feasibility in Stereo-Electroencephalography
Coelli S, Nobili L, Boly M, Riedner B, Bianchi AM.
Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:3854-3857. doi: 10.1109/EMBC.2019.8857664.
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Graph Theoretical Analysis of Cortical Networks based on Conscious Experience
Lee M, Baird B, Gosseries O, Nieminen JO, Boly M, Tononi G, Lee SW.
Annu Int Conf IEEE Eng Med Biol Soc. 2019 Jul;2019:3373-3376. doi: 10.1109/EMBC.2019.8857648.
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Electroencephalography and single-unit recordings
Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH
Award: 1K23NS112473-01A1
PI: BOLY, MELANIE
12/15/2020 - 11/30/2025
Linking altered sleep homeostasis to increased autonomic instability and SUDEP risk in patients with epilepsy
Sponsor: Lily's Grace Grant
Award: 9/1/2021
PI: BOLY, MELANIE
07/01/2020 - 06/30/2022

Lab Staff

Rosario Ciliento

Position title: Associate Research Specialist

Cole Cimoch

Position title: Research Intern

Max Grobbelaar

Position title:

Mariel Kalkach Aparicio

Position title: Research Specialist

Beril Mat

Position title: Associate Research Specialist

Michele Ravelli

Position title: Research Associate

Brinda Sevak

Position title: Research Specialist

Giulietta Vigueras

Position title: Associate Research Specialist

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