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Active Grants

Testing Direct Effects of mGluR5 Inhibition in an Alzheimer's Disease Mouse Model

NIH R21AG044714
PI: Cara Westmark, PhD
The goal of this project is to test the effect of the mGluR5 inhibitor fenobam on seizures, learning/memory and biomarker expression in Alzheimer’s disease mice.

Testing Direct Effects of mGluR5 Inhibition on Sleep in an Alzheimer’s Disease Mouse Model

ADRC Pilot Funding
PI: Cara Westmark, PhD

Preclinical Testing of Sleep-Wake Patterns as an Outcome Measure for Fragile X

PI: Cara Westmark, PhD
Study aims is to understand changes in sleep wake patterns and diurnal rhythms in Fragile X mouse model and understand the role of sleep changes in disease progression.
5/1/2016 - 4/30/2018

Preclinical Testing of BACE1 Inhibitors in Fmr1KO Mice

PI: Cara Westmark, PhD