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Active Grants

Preclinical Testing of Sleep-Wake Patterns as an Outcome Measure for Fragile X

FRAXA Research Foundation
PI: Cara Westmark, PhD
Study aims is to understand changes in sleep wake patterns and diurnal rhythms in Fragile X mouse model and understand the role of sleep changes in disease progression.
5/1/2016 - 4/30/2018

Preclinical Testing of BACE1 Inhibitors in Fmr1KO Mice

PI: Cara Westmark, PhD
The goal of this project is to treat Fmr1KO mice with a commercially available BACE1 inhibitor versus a novel BACE1/acetyltransferase (ATase) inhibitor.