MISSION STATEMENT:
The Mission of the Section of Epilepsy at the University of Wisconsin School of Medicine and Public Health is to promote the health of patients with neurological disorders. We are a group of individuals with diverse interests and the common goal to maintain excellence in clinical care, education, and research.
We are committed to the teaching of medical students and residents to be future leaders in the fields of Epilepsy and Neurology. We also aim to be the educational resource for the community and health-care providers.
The Section of Epilepsy will carry out clinical, translational and basic research in areas related to Epilepsy.
Medical Director
Providers
APPs
| Defining a Proteomic Signature for Soy-Induced Metabolic Changes in Mice Sponsor: USDA, NATL INSTITUTE FOOD & AGRICULTURE Award: 2018-67001-28266 PI: WESTMARK, CARA J 7/15/2018 - 7/14/2024 |
| Neuropsychological Progression in New Onset Epilepsy Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 2R56NS044351-12A1 PI: JONES, JANA E 4/1/2019 - 3/31/2022 |
| Circadian Timekeeping, Oxidative Stress and Metabolism in ALS Models Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 7R21NS102599-03 PI: VARGAS, MARCELO R 2/15/2020 - 4/30/2022 |
| The Juvenile Myoclonic Epilepsy Connectome Project Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 1R01NS111022-01A1 PI: STRUCK, AARON F 3/15/2020 - 1/31/2025 |
| The Juvenile Myoclonic Epilepsy Connectome Project - Garcia-Ramos Admin Supplement Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 1R01NS111022-01A1 PI: STRUCK, AARON F 7/1/2020 - 1/31/2025 |
| Preparing for preventive clinical trials in Huntington's disease Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 7U01NS105509-03 PI: PAULSEN, JANE S 4/23/2020 - 1/31/2024 |
| Statistical disease modeling and clinimetrics to prepare for preventive trials in huntington disease Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 7U01NS103475-04 PI: PAULSEN, JANE S 4/23/2020 - 3/31/2023 |
| NAD+ metabolism and signaling in ALS models Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 2R01NS089640-07 PI: VARGAS, MARCELO R 9/30/2020 - 8/31/2025 |
| Electroencephalography and single-unit recordings Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 1K23NS112473-01A1 PI: BOLY, MELANIE 12/15/2020 - 11/30/2025 |
| Role of FABP7 in ALS models Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 1R01NS122973-01 PI: VARGAS, MARCELO R 7/1/2021 - 4/30/2026 |
| Testing of Their Novel Drugs in Fmr1KO Models(FXS) Sponsor: NEURODETECTIVE INTERNATIONAL Award: PI: WESTMARK, CARA J 11/1/2018 - 10/31/2021 |
| Certified Duchenne Care Center - program support Sponsor: PARENT PROJECT MUSCULAR DYSTROPHY Award: PI: KWON, JENNIFER MEESUK 1/1/2019 - 12/31/2021 |
| DELIVER-MS Sponsor: CLEVELAND CLINIC FOUNDATION (PCORI prime sponsor) Award: MS-1610-37047 PI: FROST, NATASHA 2/1/2018 - 1/31/2023 |
| Comparative Effectiveness Randomized Trial to Improve Stroke Care Delivery: C3FIT: Coordinated, Collaborative, Comprehensive, Family-based, Integrated, and Technology-enabled Care Sponsor: VANDERBILT UNIVERSITY MEDICAL CENTER Award: VUMC72156 PI: ADELMAN, ERIC E 2/1/2019 - 1/31/2022 |
| Brain Aging in Persons with Childhood Onset Epilepsy: A Population Based Investigation II Sponsor: CITIZENS UNITED FOR RESEARCH IN EPILEPSY Award: 84626150-42313 PI: HERMANN, BRUCE P 1/1/2021 - 12/31/2021 |
| Huntington's Disease Society of America Center of Excellence Grant Sponsor: HUNTINGTONS DISEASE SOCIETY OF AMERICA Award: PI: SHANNON, KATHLEEN M 1/1/2021 - 12/31/2021 |
| Preclinical Testing of High Fat / Low Carb Diets in Fragile X Mice and Cells Sponsor: FRAXA RESEARCH FOUNDATION Award: PI: WESTMARK, CARA J 5/1/2021 - 4/30/2022 |
| Exploring the neural basis of naming impairment in patients with epilepsy Sponsor: AMERICAN EPILEPSY SOCIETY Award: PI: STRUCK, AARON F 7/1/2021 - 6/30/2022 |
| Sleep Research Program for Advancing Careers (SOAR) Sponsor: AMERICAN ACADEMY OF SLEEP MEDICINE FDN Award: PI: BAZALAKOVA, MIHAELA H 8/10/2020 - 6/16/2021 |
| Unraveling the earliest phases of vascular cognitive impairment and dementia using CADASIL--a monogenic form of small vessel cerebrovascular disease Sponsor: DHHS, PHS, NATIONAL INSTITUTES OF HEALTH Award: 1RF1AG074608-01 PI: PAULSEN, JANE S 9/30/2021 - 8/31/2024 |
| Acute Inflammation from Focal Seizures using [18F]-FEPPA PET/MR Sponsor: Lily's Grace Grant Award: 5/30/2019 PI: STRUCK, AARON F 07/01/2019 - 06/30/2022 |
| Harnessing a novel Ab40 anti-inflammatory pathway for AD intervention Sponsor: ICTR Pilot Funds Award: ICTR-UWHC RD 14 PI: HUANG, ZHEN 09/01/2020 - 01/31/2022 |
| Linking altered sleep homeostasis to increased autonomic instability and SUDEP risk in patients with epilepsy Sponsor: Lily's Grace Grant Award: 9/1/2021 PI: BOLY, MELANIE 07/01/2020 - 06/30/2022 |
| Modeling Pathogenicity and Treatment Response in Epileptic Channelopathies Sponsor: Lily's Grace Grant Award: 6/4/2021 PI: KNOX, ANDREW T 07/01/2021 - 06/30/2023 |
| Longitudinal MRI in Preclinical Parkinson Disease
Sponsor: VA Award: I01CX000555-05A1 PI: GALLAGHER, CATHERINE L 10/1/2017 - 9/30/2022 |
| Astrocyte-specific TLR4 signaling and Blood Brain Barrier permeability following acute focal cerebral Sponsor: National Institutes of Health Award: 1K08NS130144-01 PI: Famakin, Bolanle 3/1/2023 - 2/29/2024 |
Sponsor: CNS Pharmaceuticals Award: CNS-201 PI: Bhatia, Ankush 23/09/2022 - 31/12/2040 |
| ONC201 vs placebo in H3K27M-mutant diffuse midline glioma Sponsor: Chimerix, Inc. Award: ONC201-108 PI: Bhatia, Ankush 18/04/2023 - 31/12/2040 |
Sponsor: Imvax Inc. Award: 14379-201 PI: Bhatia, Ankush 31/05/2023 - 31/12/2099 |
| Lu177-DOTATATE in newly diagnosed and recurrent glioblastoma: Phase 1 Study Sponsor: Novartis Pharamaceuticals KK Award: AAA601A52101 PI: Bhatia, Ankush 01/10/2023 - 02/08/2025 |
| Pilot Study investigating the role of FAPI in glioma Sponsor: Radiology R&D/SOFIE Pharma Award: PI: - |
| Phase 3 Study randomizing patients to IV Berubicin vs PO Lomustine in 1st recurrent GBM Sponsor: Worldwide pharmaceuticals Award: PI: Bhatia, Ankush - |
| Phase 2 Study combining temozolomide with lomustine in MGMT Methylated GBM Sponsor: NRG Oncology (Cooperative Group) Award: PI: Bhatia, Ankush - |
| Phase 2 study combining Bevacizumab with Pulsed Reduced Dose Rate Radiotherapy in recurrent GBM Sponsor: Merck Award: PI: Bhatia, Ankush - |
| A Phase 2b Clinical Study With a Combination Immunotherapy in Newly Diagnosed Patients With Glioblastoma Sponsor: Imvax Award: PI: Bhatia, Ankush - |
| Sleep Deprivation Exacerbates Seizures and Diminishes GABAergic Tonic Inhibition Konduru SS, Pan YZ, Wallace E, Pfammatter JA, Jones MV, Maganti RK. Ann Neurol. 2021 Sep 2. doi: 10.1002/ana.26208. Online ahead of print. See full publication information |
| Regional and global resting-state functional MR connectivity in temporal lobe epilepsy: Results from the Epilepsy Connectome Project Struck AF, Boly M, Hwang G, Nair V, Mathis J, Nencka A, Conant LL, DeYoe EA, Raghavan M, Prabhakaran V, Binder JR, Meyerand ME, Hermann BP. Epilepsy Behav. 2021 Apr;117:107841. doi: 10.1016/j.yebeh.2021.107841. Epub 2021 Feb 18. See full publication information |
| Untangling a Web: Basic Mechanisms of the Complex Interactions Between Sleep, Circadian Rhythms, and Epilepsy Maganti RK, Jones MV. Epilepsy Curr. 2021 Mar;21(2):105-110. doi: 10.1177/1535759721989674. Epub 2021 Feb 5. See full publication information |
| Unexpected pain with electrocortical stimulation in a teenager with temporal encephalocele Swanson LC, Hsu D, Ahmed R, Brucker J, Knox AT. Epilepsy Behav Rep. 2021 Mar 31;16:100444. doi: 10.1016/j.ebr.2021.100444. eCollection 2021. See full publication information |
| Quantitative spatio-temporal characterization of epileptic spikes using high density EEG: Differences between NREM sleep and REM sleep Kang X, Boly M, Findlay G, Jones B, Gjini K, Maganti R, Struck AF. Sci Rep. 2020 Feb 3;10(1):1673. doi: 10.1038/s41598-020-58612-4. See full publication information |
| Validation of an algorithm of time-dependent electro-clinical risk stratification for electrographic seizures (TERSE) in critically ill patients Cissé FA, Osman GM, Legros B, Depondt C, Hirsch LJ, Struck AF, Gaspard N. Clin Neurophysiol. 2020 Aug;131(8):1956-1961. doi: 10.1016/j.clinph.2020.05.031. Epub 2020 Jun 23. See full publication information |
| Molecular Basis for Synaptotagmin-1-Associated Neurodevelopmental Disorder Bradberry MM, Courtney NA, Dominguez MJ, Lofquist SM, Knox AT, Sutton RB, Chapman ER. Neuron. 2020 Jul 8;107(1):52-64.e7. doi: 10.1016/j.neuron.2020.04.003. Epub 2020 May 1. See full publication information |
| Neuroticism in temporal lobe epilepsy is associated with altered limbic-frontal lobe resting-state functional connectivity Rivera Bonet CN, Hwang G, Hermann B, Struck AF, J Cook C, A Nair V, Mathis J, Allen L, Almane DN, Arkush K, Birn R, Conant LL, DeYoe EA, Felton E, Maganti R, Nencka A, Raghavan M, Shah U, Sosa VN, Ustine C, Prabhakaran V, Binder JR, Meyerand ME. Epilepsy Behav. 2020 Sep;110:107172. doi: 10.1016/j.yebeh.2020.107172. Epub 2020 Jun 14. See full publication information |
| The Johns Hopkins Neurosciences Intensive Care Nursery Tenth Anniversary (2009-2019): A Historical Reflection and Vision for the Future Carrasco M, Stafstrom CE, Tekes A, Parkinson C, Northington FJ; Johns Hopkins Neurosciences Intensive Care Nursery. Child Neurol Open. 2020 Mar 17;7:2329048X20907761. doi: 10.1177/2329048X20907761. eCollection 2020 Jan-Dec. See full publication information |
| Network, clinical and sociodemographic features of cognitive phenotypes in temporal lobe epilepsy Hermann B, Conant LL, Cook CJ, Hwang G, Garcia-Ramos C, Dabbs K, Nair VA, Mathis J, Bonet CNR, Allen L, Almane DN, Arkush K, Birn R, DeYoe EA, Felton E, Maganti R, Nencka A, Raghavan M, Shah U, Sosa VN, Struck AF, Ustine C, Reyes A, Kaestner E, McDonald C, Prabhakaran V, Binder JR, Meyerand ME. Neuroimage Clin. 2020;27:102341. doi: 10.1016/j.nicl.2020.102341. Epub 2020 Jul 10. See full publication information |
